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Combo-pilling could be the newest fad or better yet the newest to come under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that at the time of right now there are not any long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug can also raise blood pressure levels and heartrate, and really should not be used in people who have a history of cardiac event or stroke in the last six months. 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