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  • An article published on The American Journal on Addictions stated that expecting mothers who were dependent on opioids were strongly thinking about antagonist treatment, especially the one that involves the use of naltrexone to combat their abusing drugs disorder.

    Using two separate drugs to shed pounds can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err assisting caution and permit the FDA do its job and demand some study be done so the public recognizes the side effects and hazards of the medications before we drive them. Keep in mind that drug companies have been in business to generate income and that they would say everything to keep people on the medications.

    Researchers found that participants taking this drug for a year, dropped excess weight within 4 weeks and have kept the extra weight off throughout the 56 weeks with the study. Contrave is really a combination of the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which are made up of several active ingredient, which may make them more potent and safer.

    Combo-pilling could be the newest fad or also the newest ahead under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills has become popular will be the fact that at the time of right now there aren't any long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA.

    Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise blood pressure and pulse rate, and must not be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients on the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.

    "There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.